Triacsin C

Size

£607.00

SKU:: 256968
Molecular Weight:: 207.27
Purity:: ≥95%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 76896-80-5
Format:: Powder
Extra Details:: Triacsin C is a natural product that belongs to the group of macrolide antibiotics. It has been shown to inhibit the production of inflammatory cytokines and chemokines, such as tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), and IL-6, by binding to toll-like receptor 4. This drug also inhibits the production of inflammatory mediators, such as prostaglandin E2, in 3T3-L1 adipocytes. Triacsin C has also been shown to have antihypertensive effects through its ability to bind to ATP binding cassette transporters and inhibit the uptake of diacylglycerol into primary cells. In addition, triacsin C has been shown to have cardioprotective effects by reducing myocardial infarct size in mice and suppressing xenograft tumor growth through inhibition of angiogenesis. Synonyms: FR 900190; Triacsin C; WS 1228A; 2E,4E,7E-undecatrienal, nitrosohydrazone CAS No: 76896-80-5 Molecular Formula: C11H17N3O Molecular Weight: 207.27 Appearance: Powder Purity: ≥95% Solubility: DMSO: 5mg/ml; Methanol: 5mg/ml Storage and Stability: Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.