256126
Ouabain
Size
£377.00
- SKU:
- 256126
- Molecular Weight:
- 728.77
- Purity:
- ≥98%
- Storage Conditions:
- 4°C
- Supplier:
- United States Biological
- CAS Number:
- 630-60-4
- Format:
- White to off-white solid
- Extra Details:
- Ouabain is a potent inhibitor of the Na+/K+-ATPase pump in cardiac and skeletal muscles. It has been shown to inhibit signal pathways that are involved in the regulation of cellular membrane potentials, such as the michaelis–menten kinetics. Ouabain has also been found to be effective against syncytial virus infection. Ouabain inhibits viral replication by inhibiting cellular protein synthesis and reducing cell number due to its cytotoxic effects on myocardial cells. Ouabain has also been found to inhibit neuronal death induced by α1-adrenergic receptor agonists, such as p2y receptors. Synonyms: 3-(6-Deoxy-alpha-L-mannopyranosyloxy)-1,5,11a,14,19-pentahydroxycard-20(22)-enolide; Acocantherin, Astrobain, Gratibain, Gratus strophanthin, Kombetin, Ouabain; (1β,3β,5β,11α)-3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxycard-20(22)-enolide Octahydrate; g-Strophanthin Octahydrate CAS No: 11018-89-6 Anhydrous: 630-60-4 Molecular Formula: C₂₉H₄₄O₁₂•8H₂O Molecular Weight: 728.77 Appearance: White to off-white solid Purity: ≥98% Melting Point: 178-185°C Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly) Storage and Stability: Store at 4°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Ambient