S-(4-Nitrobenzyl)-6-thioinosine (NBMPR)

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£403.00

SKU:: 255954
Molecular Weight:: 419.41
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 38048-32-7
Extra Details:: S-(4-Nitrobenzyl)-6-thioinosine is a nucleoside analog and an inhibitor of the human equilibrative nucleoside transporter (hENT1) (1,2,3). Nucleoside transporter inhibitors are useful compounds to investigate anticancer, antiviral, cardioprotective, and neuroprotective agents. Synonyms: 6-S-[(4-Nitrophenyl)methyl]-6-thioinosine; 6-((4-nitrobenzyl)thio)-9-D-ribofuranosylpurine; NBTI; S-(p-Nitrobenzyl)-6-mercapto_x000B_-9-β-D-ribofuranosylpurine; NBMPR; NSC 296962 CAS No: 38048-32-7 Molecular Formula: C₁₇H₁₇N₅O₆S Molecular Weight: 419.41 Purity (HPLC): ≥99% Appearance: Off-white to white solid Melting Point: 177-180°C (lit) Solubility: DMSO to 100mM Freshly made daily. Method for Determining Identity: Proton NMR and Mass Spectrometric Analysis Elemental Analysis: Calculated: %C; 48.68, %H: 4.09, %N: 16.70 Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at 4°C. Reconstitute with sterile DMSO. Do not freeze. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.