N1,N12-Diethylspermine Tetrahydrochloride

Size

£351.00

SKU:: 255933
Molecular Weight:: 404.29
Purity:: ≥95% (HPLC)
Storage Conditions:: RT
Supplier:: United States Biological
CAS Number:: 113812-15-0
Format:: White to off-white powder
Extra Details:: N1, N12-Diethylsperminemiddot4HCl is an inhibitor of polyamine synthesis. A polyamine derivative with ethyl modifications at the terminal nitrogen atoms (N1 and N12) of spermine; Tetrahydrochloride salt form enhances stability and solubility for experimental use. Used in studies of polyamine metabolism, cell proliferation, and nucleic acid interactions. Modulates enzyme activity (e.g., spermidine/spermine acetyltransferases). Serves as a component in non-viral transfection systems due to its cationic nature, aiding DNA/RNA condensation. Investigated for its role in apoptosis regulation and as a potential chemotherapeutic agent targeting polyamine pathways. Polyamine analogs like this compound may exhibit activity against bacteria or parasites by disrupting ion channels. Synonyms: N~1~,N~4~-bis[3-(ethylamino)propyl]-1,4-butanediamine tetrahydrochloride; N,N'-bis[3-(ethylamino)propyl]butane-1,4-diamine;tetrahydrochloride CAS No: 113812-15-0 Molecular Formula: C14H38Cl4N4 Molecular Weight: 404.29 Appearance: White to off-white powder Purity: ≥95% (HPLC) Solubility: Water, methanol, DMSO; slightly soluble in organic solvents. Storage and Stability: May be stored at RT.