Alendronate sodium (MK 217)

Size

£306.00

SKU:: 255832
Molecular Weight:: 271.08
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 129318-43-0
Extra Details:: Osteoclast-mediated bone resorption inhibitor. Binds and blocks farnesyl diphosphate synthase (FPPS) in the HMG-CoA pathway (IC50 = 460nM for recombinant human FPPS); causes macrophage apoptosis. Inhibits prenylation and sterol biosynthesis in purified osteoclasts. Solubility: 50mM in water