LY 364947

Size

£381.00

SKU:: 255730
Molecular Weight:: 272.3
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 396129-53-6
Extra Details:: Selective inhibitor of TGF-β type-I receptor (TGF-β RI, TGFR-I, TβR-I, ALK-5) (IC50 values are 59, 400 and 1400nM for TGR-β RI, TGF-β RII and MLK-7K respectively). Inhibits TGF-β-dependent luciferase production in mink lung cells (p3TP lux) and growth in mouse fibroblasts (NIH 3T3) (IC50 values are 47 and 89nM respectively). Suppresses invasion of MDA-MB-231 breast cancer cells in a matrigel invasion assay. CAS No: 396129-53-6 Purity: ≥98% Solubility: Soluble to 100mM in DMSO Storage: Store at RT, Store in the dark under inert atmosphere.