255613
KU 0060648
Size
£523.00
- SKU:
- 255613
- Molecular Weight:
- 582.71
- Purity:
- ≥97%
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- CAS Number:
- 881375-00-4
- Format:
- Supplied as a beige solid.
- Extra Details:
- Dual PI 3-K and DNA-PK inhibitor (IC50 values are <0.1, 0.5, 4 and 19 nM for PI 3-Kdelta, PI 3-Kbeta, PI 3-Kalpha and DNA-PK respectively). Inhibits proliferation of MCF7 cells in vitro and delays growth of MCF7 xenografts in mice. Also enhances CRISPR-Cas9-mediated homology- directed repair (HDR) efficiency, and attenuates nonhomologous end-joining (NHEJ). Synonyms: 4-Ethyl-N-[4-[2-(4-morpholinyl)-4-o xo-4H-1-benzopyran-8-yl]-1-dibenzothienyl]-1-piper azineacetamide CAS No: 881375-00-4 Molecular Formula: C₃₃H₃₄N₄O₄S Molecular Weight: 582.71 Appearance: Supplied as a beige solid. Purity: ≥97% Solubility: Soluble to 100mM in 2eq.HCl Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Blue Ice