Desformylflustrabromine hydrochloride

Size

£408.00

SKU:: 255126
Molecular Weight:: 357.72
Purity:: ≥98% (HPLC)
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 951322-11-5
Format:: White to off-white solid
Extra Details:: Positive allosteric modulator of nicotinic α4β2 receptors; selectively increases the ionic current through α4β2 in the presence of ACh. Displays 14.7-fold selectivity for α4β2 over homomeric (α7) receptors. Moderately cytotoxic in HCT-116 cells. Also inhibits human muscle (αβεδ) and Torpedo (αβγδ) nAChRs (IC50 values are 1.0 and 0.1 μM, respectively) by binding in the ion channel. Synonyms: 6-Bromo-2-(1,1-dimethyl-2-propenyl)-N-1H-indole-3-ethanamine hydrochloride CAS Number: 951322-11-5 Molecular Formula: C16H21BrN2.HCl Molecular Weight: 357.72 Appearance White to off-white solid Purity: ≥98% (HPLC) Solubility: DMSO 35.77mg/ml (100mM) Water 3.58mg/ml (10mM) with gentle warming Storage 4°C. Hygroscopic. Keep tightly closed and desiccated. Light sensitive.