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255063

Cyclic Pifithrin-α hydrobromide

Size

£417.00

SKU:
255063
Purity:
≥98%
Storage Conditions:
4°C
Supplier:
United States Biological
CAS Number:
511296-88-1
Extra Details:
Cyclic analog of pifithrin-α , a small molecule inhibitor of p53. Prevents dexamethasone-induced cell death in murine thymocytes (EC50 = 2.01uM). Sensitizes p53-deficient tumors to radiotherapy and chemotherapy; increases apoptosis in target cells when used in combination with antimicrotubule agents. CAS Number: 511296-88-1 Synonyms: 5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazole hydrobromide, Pifithrin-β Molecular Formula: C16H16N2S.HBr Molecular Weight: 349.29 Solubility: 100mM in DMSO and to 10mM in ethanol Purity: ≥98% Storage and Stability: Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Shipping Conditions:
Blue Ice