255056
Cucurbitacin I
Size
£1,272.00
- SKU:
- 255056
- Molecular Weight:
- 514.65
- Purity:
- ≥95%
- Storage Conditions:
- 4°C
- Supplier:
- United States Biological
- CAS Number:
- 2222-07-3
- Format:
- White solid
- Extra Details:
- Cucurbitacin I is a selective inhibitor of STAT3/JAK2 signaling. Inhibits the activation of STAT3 and JAK2 and displays no activity on Src, Akt, ERK and JNK. Suppresses phosphotyrosine levels of STAT3, inhibits STAT3 DNA binding and STAT3-mediated gene expression. Induces apoptosis in cell lines expressing constitutively active tyrosine-phosphorylated STAT3. Synonyms: (9β,10α,16α,23E)-2,16,20,25-Tetrahydroxy-9-methyl-19-norlanosta-1,5,23-triene-3,11,22-trione; Elatericin B,JSI 124 CAS No: 2222-07-3 Molecular Formula: C30H42O7 Molecular Weight: 514.65 Appearance: White solid Purity: ≥95% Solubility: DMSO: 10mM; Chloroform, Dichloromethane, Ethyl Acetate, Acetone Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Blue Ice