CRT 0066101

Size

£492.00

SKU:: 255050
Molecular Weight:: 411.33
Purity:: ≥98%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 1883545-60-5
Format:: Yellow solid
Extra Details:: Potent inhibitor of protein kinase D (PKD); inhibits all PKD isoforms (IC50 values are 1, 2 and 2.5nM for PKD1, PKD3 and PKD2 respectively). Exhibits selectivity for PKD against a panel of >90 protein kinases, including PKC-alpha, MEK, ERK, c-Raf and c- Src. Reduces proliferation and cell viability of pancreatic cancer cells expressing moderate levels of endogenous PKD1/2. Orally bioavailable. Appearance: Yellow solid Purity: ≥98% Solubility: Soluble in water to 20mM and soluble in DMSO to 10mM Method for Determining Identity: Proton NMR and MS Elemental Analysis: Calculated: 50.35% C; 6.1% H; 19.57% N Found: As reported Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.