CGS 19755

Size

£462.00

SKU:: 254949
Molecular Weight:: 223.16
Purity:: ≥95%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 110347-85-8
Format:: White to off-white powder
Extra Details:: CGS 19755 is a low-potency compound that has been investigated for its potential use in the treatment of neurodegenerative diseases. It is a selective, non-competitive antagonist of the metabotropic glutamate receptor type 2 (mGluR2) which has shown to reduce neuronal death and improve motor function in experimental models. CGS 19755 has also been shown to have no significant side-effect profiles in humans and has been tested as a pharmacological agent for the treatment of Parkinson's disease. The major analytical method used to measure the potency of CGS 19755 is intracellular Ca2+ levels. Synonyms: (2S,4R)-4-(phosphonomethyl)piperidine-2-carboxylic acid CAS No: 110347-85-8 Molecular Formula: C7H14NO5P Molecular Weight: 223.16 Appearance: White to off-white powder Purity: ≥95% Solubility: Water: 25mM Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.