CEP 1347

Size

£648.00

SKU:: 254917
Molecular Weight:: 624.77
Purity:: ≥97% (HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 156177-65-0
Format:: Supplied as a white solid
Extra Details:: Inhibitor of c-jun N-terminal kinase (JNK) signaling. Rescues motor neurons undergoing apoptosis (EC50 = 20nM). Blocks Aβ-induced cortical neuron apoptosis (EC50 ~51nM). Does not inhibit ERK1 activity. Neuroprotective. Synonym: (9S,10R,12R)-5-16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester CAS Number: 156177-65-0 Molecular Formula: C33H33N3O5S2.1⁄2H2O Molecular Weight: 624.77 Purity: ≥97% (HPLC) Form: Supplied as a white solid Solubility: DMSO to 10mM Microanalysis: Calculated: %C: 63.44, %H: 5.49, %N: 6.73 TLC: Rf=0.7 (Dichloromethane: Methanol [9:1]) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.