254353
2-APB
Size
£288.00
- SKU:
- 254353
- Purity:
- ≥98%
- Storage Conditions:
- 4°C
- Supplier:
- United States Biological
- CAS Number:
- 524-95-8
- Extra Details:
- A functional and membrane permeable D-myo-inositol 1,4,5-trisphosphate (IP3) receptor antagonist (IC50 = 42uM). Stimulates store-operated calcium (SOC) release at low concentrations (< 10uM) and inhibits it at higher concentrations (up to 50uM). Increases STIM-Orai channel conductance and limits ion selectivity. Modulator of TRP channels; blocks TRPC1, TRPC3, TRPC5, TRPC6, TRPV6, TRPM3, TRPM7, TRPM8 and TRPP2 and at higher concentrations stimulates TRPV1, TRPV2 and TRPV3. Also blocks specific gap channel subtypes. CAS Number: 524-95-8
- Shipping Conditions:
- Blue Ice