187-1, N-WASP inhibitor

Size

£471.00

SKU:: 254349
Molecular Weight:: 1784.13
Purity:: ~99% (HPLC)
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 380488-27-7
Format:: Supplied as a white lyophilized solid.
Extra Details:: Inhibits neural Wiskott-Aldrich syndrome protein (N-WASP) by stabilizing the autoinhibited state of the protein. Blocks phosphatidylinositol 4,5-bisphosphate (PIP2)-stimulated actin assembly (IC50 ~ 2 uM) but does not directly inhibit actin polymerization. CAS Number: 380488-27-7 Molecular Weight: 1784.13 Molecular Formula: C96H122N18O16 Sequence: KFPFFPQ KFPFFPQ (Modifications: Phe-2 = D-Phe, Pro-3 = D-Pro, Phe-4 = D-Phe, Pro-6 = D-Pro, Cyclized) Solubility: Soluble to 2mg/ml in water Method for Determining Identity: Mass Spectrometric Analysis Net Peptide Content: 79% Counter Ion: TFA Appearance: Supplied as a white lyophilized solid. Purity: ~99% (HPLC) Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.