10Panx

Size

£351.00

SKU:: 254341
Molecular Weight:: 1242.37
Purity:: ~96% (HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 955091-53-9
Format:: Supplied as a white lyophilized solid.
Extra Details:: Panx-1 mimetic inhibitory peptide that blocks pannexin-1 gap junctions. Inhibits P2X7-mediated dye uptake, ATP-mediated IL-1β release and caspase-1 activation without altering membrane current in macrophages in vitro. Also blocks activation of NMDA receptor secondary currents (I2nd) by >70%. CAS Number: 955091-53-9 Molecular Weight: 1242.37 Molecular Formula: C58H79N15O16 Sequence: WRQAAFVDSY Solubility: Soluble to 1mg/ml in water Method for Determining Identity: Mass Spectrometric Analysis Net Peptide Content: 91% Counter Ion: TFA Appearance: Supplied as a white lyophilized solid. Purity: ~96% (HPLC) Storage and Stability: Lyophilized and reconstituted products may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.