RON Receptor Tyrosine Kinase (c met Related Tyrosine Kinase, CD136, CD136 antigen, CDw136, Macrophage Stimulating 1 Receptor (c met Related Tyrosine Kinase), Macrophage Stimulating 1 Receptor, Macrophage Stimulating Protein Receptor alpha chain, MACROPHAGE)

Size

£731.00

SKU:: 254286
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: NIH3T3 cells expressing human RON
Clone:: Zt/f2
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Applications: Suitable for use in Immunofluorescence, ELISA, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Hybridoma: S-p2 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.