254261
PTPRB (PTPRB, HPTP BETA, HPTPB, Phosphacan Receptor TypeB, Protein Tyrosine Phosphatase Receptor Type B, PTPB, PTPRB, R PTP BETA, RPTPB)
Size
£563.00
- SKU:
- 254261
- Purity:
- Supernatant
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Embryonic rat brain proteoglycans
- Clone:
- 122.2
- Format:
- Supplied as a liquid in PBS.
- Extra Details:
- PTPRB is a member of the protein tyrosine phosphatase (PTP) family. The family comprises at least 37 proteins characterized by a catalytic phosphatase domain of approximately 240aa and includes both transmembrane and cytosolic enzymes. PTP1B is a transmembrane PTP The PTPs have high substrate specificity for phosphotyrosyl proteins at the primary sequence level sharing little similarity with the protein serine phosphatases protein threonine phosphatases or the acid and alkaline phosphatases. PTP beta interacts with and regulates the tyrosine phosphorylation level of catenins which are critical in physiological and pathological events such as cell migration adhesion and transformation. Applications: Suitable for use in Immunofluorescence, Western Blot, Immunoprecipitation, Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000-1:2500. Predicted molecular weight: 224kD Optimal dilutions to be determined by the researcher. Hybridoma: P3X myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice