PP2A B´/B56 delta (PP2A B, PP2A beta, PP2Ac, Protein Phosphatase 2 (formerly 2A) Catalytic Subunit alpha isoform, Protein Phosphatase 2 (formerly 2A) Catalytic Subunit beta isoform, Protein Phosphatase 2)

Size

£731.00

SKU:: 254247
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: GST-N-terminal fragment of human B´/B56 delta
Clone:: H5D12
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: Type 2 protein phosphatases are serine/threonine phosphatases which can preferentially dephosphorylate the alpha subunit of phosphorylase kinase and are insensitive to inhibitor 2 treatment. Protein phosphatase 2A (PP2A) can be distinguished from PP2B and PP2C which require Ca2+ and Mg2+, respectively, by its partial activity in the absence of divalent cations. PP2A activity is potently inhibited by treatment with okadaic acid and shows much stronger activity toward histone phosphorylated by Protein Kinase C and casein phosphorylated by Protein Kinase A than other protein phosphatases. Applications: Suitable for use in Western Blot, Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: 1:4000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.