PDE4A (cAMP specific 3 5 cyclic phosphodiesterase 4A, cAMP specific phosphodiesterase, DPDE2, Dunce like phosphodiesterase E2, PDE 4A, PDE4, PDE46, PDE4A11, Phosphodiesterase 4A, Phosphodiesterase 4A cAMP specific, Phosphodiesterase E2 duncehomolog, Phosphodiesterase Type 4A11) (Not for Export EU)

Size

£731.00

SKU:: 254228
Purity:: Serum
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide, corresponding to a C-terminal region common to all 4A isoforms of Human PDE4A
Format:: Supplied as a liquid.
Extra Details:: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. Applications: Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:2000. Predicted molecular weight: 98kD Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.