ORC2 (ORC2L, Origin of replication 2 (yeast Homolog) like, Origin recognition Complex Subunit 2isoform B, Origin recognition Complex Subunit 2 like (yeast), Origin recognition Complex, Subunit2, S. cerevisiae, Homolog of, Origin recognition Complex, Subunit 2-like (S. cerevisiae))

Size

£563.00

SKU:: 254204
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rat
Immunogen:: Full length protein (Human): ORC2 (hsORC)
Clone:: 3G6
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. ORC2L is a subunit of the ORC complex ORC2L forms a core complex with ORC3L 4L and 5L. It also interacts with CDC45L and MCM10 which are proteins known to be important for the initiation of DNA replication. ORC2L specifically associate with the origin of replication of Epstein Barr virus in human cells and is thought to be required for DNA replication from viral origin of replication. Applications: Suitable for use in Western Blot, Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: Use at 1:1000. Predicted molecular weight: 66kD Optimal dilutions to be determined by the researcher. Hybridoma: P3X63-Ag8.653 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice