254129
Kallikrein 2 (Hk2, hK2, KLK2A 2, KLK2A2, Tissue kallikrein 2, Glandularkallikrein 2, hGK 1, Kallikrein 2 Prostatic, KLK 2, MGC12201) (HRP)
Size
£774.00
- SKU:
- 254129
- Purity:
- Purified by Protein G affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Line tumor cells expressing hK2
- Clone:
- 6B7
- Format:
- Supplied as a liquid in PBS, 0.01% Thiomersal. Labeled with horseradish peroxidase (HRP).
- Extra Details:
- Kallikreins (KLKs) are a subgroup of trypsin-like serine proteases and are implicated in carcinogenesis. Kallikrein 2 is most closely related to Kallikrein 3 (PSA) with 78 identity and with kallikrein 1 at 68 identity. Like Kallikrein 3 Kallikrein 2 is found in greatest abundance in the prostate but at much lower levels than Kallikrein 3. In addition Kallikrein 2 seems to be more labile than Kallikrein 1 or Kallikrein 3 and is often found in a cleaved form. Kallikrein 2 is inhibited by Protein C Inhibitor (PCI). Applications: Suitable for use in ELISA, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Hybridoma: Spleen cells from immunized BALB/c.PSA. Transgenic mice were fused with the P3 myeloma cell line. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice