CD41 (CD41, CD41B, GP2B, GPalpha IIb, GPIIb, GTA, HPA3, integrin alpha 2b, Integrin alpha-IIb, Integrin alpha-IIb heavy chain, Integrin alpha-IIb light chain, form 1, Integrin alpha-IIb light chain, form 2, integrin, alpha 2b (platelet Glycoprotein IIb of IIb/IIIa Complex, antigen CD41), ITA2B, ITGA2B, ITGAB, platelet fibrinogen Receptor, alpha Subunit, Platelet Membrane Glycoprotein IIb, platelet-specific antigen BAK)

Size

£731.00

SKU:: 253979
Purity:: Purified by Protein A affinity chromatography from tissue culture supernatant.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Homogenized human medulloblastoma tissue.
Clone:: M148
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: Integrin alpha 2b, a 110-130kD transmembrane protein that is also known as CD41. CD41 associates with the integrin CD61 to form the CD41/CD61 (GPIIb/IIIa) heterodimer, a fibronectin receptor expressed in platelets. The antibody binds to some medulloblastoma and neuroblastoma cells and rhabdomyosarcoma and certain other solid tumors. No binding is observed to marrow constituents other than platelets and megakaryocytes. The antibody prevents aggregation of platelets. Applications: Suitable for use in Immunofluorescence, Flow Cytometry, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Hybridoma: P3X63-Ag8.653 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.