BRIT1 (MCT, BRIT1, FLJ12847, MCPH1, Microcephalin)

Size

£731.00

SKU:: 253949
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein MCPH1 polypeptides
Clone:: AB11
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. Applications: Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunoprecipitation, Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Immunofluorescence: 1:50-1:200 Optimal dilutions to be determined by the researcher. Hybridoma: Sp2 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.