Erythromycin

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£186.00

SKU:: 237532
Molecular Weight:: 733.98
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 114-07-8
Extra Details:: Erythromycin displays bacteriostatic activity or inhibits growth of bacteria, especially at higher concentrations,[25] but the mechanism is not fully understood. By binding to the 50s subunit of the bacterial rRNA complex, protein synthesis and subsequent structure and function processes critical for life or replication are inhibited.[25] Erythromycin interferes with aminoacyl translocation, preventing the transfer of the tRNA bound at the A site of the rRNA complex to the P site of the rRNA complex. Without this translocation, the A site remains occupied, thus the addition of an incoming tRNA and its attached amino acid to the nascent polypeptide chain is inhibited. This interferes with the production of functionally useful proteins, which is the basis of this antimicrobial action. Synonyms: E-Base; E-Mycin; Erytromycin A; Aknemycin; Aknin; emgel; Ery-Derm; Erymax; Ery-Tab; Erythromid; ERYC CAS No: 114-07-8 Molecular Formula: C₃₇H₆₇NO₁₃ Molecular Weight: 733.98 Purity: 85.0-100.5% (Dry basis) Appearance: White or almost white crystalline powder Water (Karl Fisher): ≤10% Optical Rotation [a]D20: -71° to -78° Residual Solvents: Methylene Chloride: Not Detected Related Substances: Erythromycin A enol ether: ≤3% Residue On Ignition: ≤0.2% Limit of Thiocynate: ≤0.3% Storage and Stability: Powder is stable for 6 months after receipt at 4°C.

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