236779
Calcium D-Saccharate Tetrahydrate, 98.5-102.0% USP
Size
£192.00
- SKU:
- 236779
- Molecular Weight:
- 320.26
- Purity:
- 98.5-102.0% (Titration)
- Storage Conditions:
- RT
- Supplier:
- United States Biological
- CAS Number:
- 5793-89-5
- Format:
- White crystalline powder
- Extra Details:
- Calcium D-glucarate is the calcium salt form of D-glucaric acid.1 D-Glucaric acid is an end product of D-glucuronic acid metabolism in mammals that has also been found in fruits and vegetables and has anticancer activity.2 It is produced by the oxidation of D-glucuronic acid and is a precursor in the biosynthesis of the β-glucuronidase inhibitor D-glucaro-1,4-lactone (D-saccharic acid 1,4-lactone) in vivo.1 Dietary administration of calcium D-glucarate (10% w/w) reduces tumor growth in a rat model of mammary tumorigenesis induced by 7,12-dimethylbenz[a]anthracene (DMBA).3 Urinary D-glucaric acid levels have been used as a marker for xenobiotic-induced phase II metabolism in patients with rheumatoid arthritis or individuals exposed to environmental toxicants.4,5 Synonyms: Calcium D-Saccharate; D-Glucaric Acid Calcium Salt; D-Saccharic Acid Calcium Salt CAS No: 5793-89-5 Molecular Formula: C6H8O8•Ca [4H2O] Molecular Weight: 320.26 Appearance: White crystalline powder Purity: 98.5-102.0% (Titration) Infrared Spectrum: Conforms to structure Optical Rotation: [a]D20 = +18.5 to 22.5º (C=1 in 5N HCl) Heavy Metals: ≤0.002% Chloride: ≤0.07% Sulfate: ≤0.12% Calcium: Positive test Reducing Substances: Sucrose & Reducing sugar: Should be absent Solubility: Soluble in calcium gluconate solution Methanol: slightly soluble PBS (pH 7.2): slightly soluble Storage and Stability: May be stored at RT.
- Shipping Conditions:
- Ambient