Biotinyl-e-aminocaproic acid-N-hydroxysuccinimide Ester

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£269.00

SKU:: 235549
Molecular Weight:: 454.54
Purity:: ≥97% (Assay)
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 72040-63-2
Format:: White powder
Extra Details:: Biotin-C5-NHS Ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. Synonyms: Biotinyl-ε-aminocaproic acid-N-hydroxysuccinimide ester; Biotinamidocaproate-N-hydroxysuccinimide ester; Succinimidyl 6-[biotinamido]hexanoate; Enzotin CAS No: 72040-63-2 Molecular Formula: C20H30N4O6S Molecular Weight: 454.54 Appearance: White powder Purity: ≥97% (Assay) 1H NMR, MS: Conforms to reference Solubility: DMSO: 100mg/ml (220mM); Use ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, use newly opened DMSO. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.