234678
6-Diazo-5-oxo-L-norleucine
Size
£294.00
- SKU:
- 234678
- Molecular Weight:
- 171.15
- Purity:
- ≥95%
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- CAS Number:
- 157-03-9
- Format:
- White to off-white powder
- Extra Details:
- 6-Diazo-5-oxo-L-nor-Leucine (DON) is a glutamine analog that inhibits glutaminases (Ki = 6 µM) and other glutamine-utilizing enzymes, including cytidine triphosphate synthase (CTPS), which uses glutamine in the synthesis of CTP.1,2,3 DON is commonly used in cells or tissues but its use in whole animals is limited by its teratogenicity.3,4,5 Synonyms: DON; NSC 7365 CAS No: 157-03-9 Molecular Formula: C₆H₉N₃O₃ Molecular Weight: 171.15 Appearance: White to off-white powder Purity: ≥95% Melting Point: 129-131°C Solubility: DMSO (Slightly, Heated, Sonicated), Water (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Ambient