4-Naphthalen-2-yl-thiazol-2-yl-amine

Size

£208.00

SKU:: 233415
Molecular Weight:: 226.3
Purity:: ≥98%
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 21331-43-1
Format:: Cream color amorphous powder
Extra Details:: 4-Naphthalen-2-yl-thiazol-2-yl-amine is a naphthalene derivative which has been shown to be active against gram-negative bacteria. It inhibits bacterial growth by binding to the ribosomes and preventing protein synthesis. The antibiotic binds to the dihedral site of the 30S ribosomal subunit and stabilizes the binding of ciprofloxacin, an antibiotic that inhibits bacterial DNA synthesis. 4NTZ2A has also been shown to have antifungal activity, inhibiting cell growth in Candida albicans, Saccharomyces cerevisiae and Cryptococcus neoformans. This drug also has antibacterial activity against gram-negative bacteria such as Escherichia coli, Proteus vulgaris and Salmonella typhimurium. Synonyms: 2-Amino-4-(2-naphthyl)thiazole; 2-Thiazolamine, 4-(2-naphthalenyl)-Thiazole; 2-amino-4-(2-naphthyl)-4-(2-Naphthalenyl)-2-thiazolamine; 2-Amino-4-β-naphthylthiazole CAS No: 21331-43-1 Molecular Formula: C13H10N2S Molecular Weight: 226.30 Appearance: Cream color amorphous powder Purity: ≥98% Melting Point: 152-155°C Solubility: As reported Storage and Stability: Store at 4°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.