4-Iodo-L-Phenylalanine (H-Phe(4-I)-OH)

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£257.00

SKU:: 233269
Molecular Weight:: 291.1
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 24250-85-9
Extra Details:: 4-Iodo-L-phenylalanine is an unlabeled amino acid that has been shown to inhibit the protein synthesis of cancer cells. It binds to the thrombin receptor and inhibits the activation of proteases, thereby inhibiting cancer cell growth. 4-Iodo-L-phenylalanine also inhibits translation by binding to the ribosome during the translation process and binding to the hydroxyl group on a mRNA molecule during transcription. This inhibition leads to a decrease in protein synthesis and cell proliferation. Synonyms: H-Phe(4-I)-OH; S)-2-Amino-3-(4-iodophenyl)propanoic acid CAS No: 24250-85-9 Molecular Formula: C9H10INO2 Molecular Weight: 291.10 Purity: ≥98% (HPLC, Chiral) Appearance: White powder Melting Point: ~240°C (lit) Optical Rotation: [a]D20 = -6.5 ± 2º (C=2 in 80% AcOH) Solubility: Partly miscible with water. D-Enantiomer: 0.02% Method of Determining Identity: Proton NMR and Mass Spectroscopic and Mass Spectrometric Analysis Loss on Drying: As Reported Infared Spectrum: Conforms Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.