IL-1 beta, Recombinant, Mouse, BSA-free (Interleukin 1 beta, IL1B, IL-1F2)

Size

£678.00

SKU:: 228352
Molecular Weight:: 17
Purity:: ≥97% (SDS-PAGE, reducing conditions and visualized by silver stain)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in PBS.
Extra Details:: IL-1 is a name that designates two proteins, IL-1 alpha and IL-1 beta, that are the products of distinct genes, but recognize the same cell surface receptors. IL-1 alpha and IL-1 beta are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. Source: E. coli,; Val118-Ser269 with an N-terminal Met Molecular Weight: ~17kD Biological Activity: Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. The ED50 for this effect is typically 2-10pg/ml. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.