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228230

Interleukin-2 (IL-2) (PE)

Size

£448.00

SKU:
228230
Purity:
Purified
Storage Conditions:
4°C Do Not Freeze
Supplier:
United States Biological
Host:
Rat
Immunogen:
Recombinant protein corresponding to mouse IL-2 expressed in E. coli.
Clone:
JES6-5H4
Format:
Supplied as a liquid in PBS, 0.09% sodium azide and a stabilizer. Labeled with R-Phycoerythrin (PE).
Extra Details:
IL-2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cy- tokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. Applications: Suitable for use in Flow Cytometry, ELISA. Other applications not tested. Recommended Dilution: Flow Cytometry: 1ug/10e6 cells Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Shipping Conditions:
Blue Ice