228158
CD71 (T9, Transferrin Receptor, TfR) (Low Endotoxin, Azide-Free)
Size
£473.00
- SKU:
- 228158
- Purity:
- Purified
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rat
- Immunogen:
- DMSO induced Friend erythroleukemia 745.6.
- Clone:
- RI7217 (2Q1680)
- Format:
- Supplied as a liquid in PBS.
- Extra Details:
- CD71, a type II transmembrane glycoprotein expressed on the cell surface as a homodimer, is the transferrin receptor. the growth of normal and neoplastic cells. It is expressed at low levels on resting B and T lymphocytes but is upregulated during responses to antigens and mitogens presumably reflecting the iron dependence of proliferation. Its expression declines with maturation and differentiation. CD71 plays a critical role in cell proliferation by controlling the supply of iron which is essential for many metabolic pathways through the binding and endocytosis of transferrin, the major iron-carrying protein. It may also be involved in signal transduction via its association with the T cell receptor z chain. A The monoclonal antibody inhibits cell proliferation in vitro. Applications: Suitable for use in Flow Cytometry, Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice