Troponin I

Size

£521.00

SKU:: 227214
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: 2-8°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Cardiac Troponin I.
Clone:: 15B488
Format:: Supplied as a liquid in 10mM PBS, pH 8.0, 0.05% sodium azide.
Extra Details:: Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. Applications: Suitable for use in ELISA and Lateral Flow. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.