226861-APC

CA 15-3 (Breast Tumor. 15-3, MUC1, MUC-1) (APC)

Size

£1,829.00

SKU:: 226861-APC
Application:: FLISA
Purity:: Purified by Protein A affinity chromatography
Storage Conditions:: 4°C Do Not Freeze
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Human CA15-3 from human cell line
Clone:: 15B298
Format:: Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Extra Details:: CA 15-3 (or MUC1) is the most widely used serum marker in breast cancer. MUC1 appears to play a role in cell adhesion and the high levels present in cancer may be causally involved in metastasis. MUC1 is a large transmembrane glycoprotein which is frequently overexpressed and aberrantly glycosylated in cancer. CA 15-3 is a preclinicla marker for recurrent breast cancer and is used to monitor treatment of patients with advanced breast cancer. Applications: Suitable for use in FLISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.