226821
Boc-Leu-Arg-Arg-AMC (Boc-LRR-AMC, Proteasome Substrate)
Size
£247.00
- SKU:
- 226821
- Molecular Weight:
- 773.8365
- Purity:
- ≥98%
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- CAS Number:
- 109358-46-5 (free base)
- Format:
- Supplied as a solid lyophilized powder.
- Extra Details:
- Fluorogenic tri-peptide substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. Substrate for the Kex2 endopeptidase from S. Cervisiae, which has substrate specificity toward the C-terminal side of LR, PR and RR sequences. Can be cleaved by Kallikrein 5 with a P1 site preference for basic residues (R and K). This substrate is useful for inhibitor screening and kinetic analysis. CAS Number: 109358-46-5 (free base) Source: Synthetic Excitation: Excitation: 380nm. Emission: 460nm. Use: Add from DMSO stock directly to in vitro or in vivo assay at desired concentration. Typical concentrations range from 10-100uM. Molecular Formula: C33H52N10O7 . HCl Molecular Weight: 773.8 . 36.5 Sequence: Boc-Leu-Arg-Arg-7-amido-4-methylcoumarin Solubility: 5% acetic acid Purity: ≥98% Appearance: Supplied as a solid lyophilized powder. Storage and Stability: Stable for at least 1 year after receipt when stored at -20°C.
- Shipping Conditions:
- Blue Ice