TCF-3 (Transcription Factor E2-alpha, Class B basic Helix-Loop-Helix Protein 21, bHLHb21, Immunoglobulin Enhancer-Binding Factor E12/E47, Immunoglobulin Transcription Factor 1, Kappa-E2-Binding Factor, Transcription Factor 3, TCF-3, Transcription Factor ITF-1, TCF3, BHLHB21, E2A, ITF1)

Size

£672.00

SKU:: 226228
Application:: IHC-Fr
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to amino acids 570-620 of human TCF-3.
Format:: Supplied as a liquid PBS, pH 7.2, 0.02% sodium azide, 50% glyecrol.
Extra Details:: Heterodimers between TCF3 and tissue specific basic helix loop helix (bHLH) proteins play major roles in determining tissue specific cell fate during embryogenesis, like muscle or early B cell differentiation. Dimers bind DNA on E box motifs: 5' CANNTG 3'. Binds to the kappa E2 site in the kappa immunoglobulin gene enhancer. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (Paraffin): 1:50-1:200 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.