220890

ASS1 (Argininosuccinate Synthase, Citrulline-aspartate Ligase, ASS1, ASS)

Size

£512.00

SKU:: 220890
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to full length human ASS1. UniProt Accession: P00966.
Format:: Supplied as a liquid PBS, 0.09% sodium azide, 50% glycerol.
Extra Details:: ASS1, also known as argininosuccinate synthase or citrulline-aspartate ligase, belongs to the argininosuccinate synthase family. ASS1 is an urea cycle enzyme with a tetrameric structure composed of identical subunits. It is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. A deficiency of ASS1 causes citrullinemia (CTLN1), an autosomal recessive disease which is characterized by severe vomiting spells and mental retardation. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:500-1:2000 Immunohistochemistry: 1:50-1:200 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.