KCNMB3, Recombinant, Human, aa82-207, His-Tag (Calcium-Activated Potassium Channel Subunit beta-3 Isoform D, Potassium Large Conductance Calcium-Activated Channel, Subfamily M, Beta Member 3)

Size

£512.00

SKU:: 218281
Molecular Weight:: 16.8
Purity:: ≥85% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.4M urea, 10% glycerol.
Extra Details:: The KCNMB3 is one of a family of four auxiliary beta subunits found in the mammalian genome that associate with Slo1 alpha subunits and regulate BK channel function. In humans, the KCNMB3 gene contains four N-terminal alternative exons that produce four functionally distinct beta3 subunits, beta3a-d. Three variants, beta3a-c, exhibit kinetically distinct inactivation behaviors. Source: Recombinant protein corresponding to aa82-207 from human KCNMB3, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~16.8kD (149aa) Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.