GZMB, Recombinant, Human, aa21-247, His-Tag (Granzyme B)

Size

£512.00

SKU:: 218207
Molecular Weight:: 27.8
Purity:: ≥85% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM Tris, pH 8.0, 10% glycerol
Extra Details:: GZMB, also known as granzyme B, is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface nonself antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Source: Recombinant protein corresponding to aa21-247 from human GZMB, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~27.8kD (248aa) Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.