GDF5, Recombinant, Mouse, aa376-495, His-Tag (Growth/Differentiation Factor 5 Precursor)

Size

£512.00

SKU:: 218177
Molecular Weight:: 16
Purity:: ≥90% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 10% glycerol.
Extra Details:: Growth/differentiation factor 5 precursor, also known as GDF5, is a member of the TGF superfamily. GDF5 has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. GDF5 mutations have been identified in mice with the mutation brachypodism (bp), a mutation which affects the length and number of bones in limbs. Source: Recombinant protein corresponding to aa376-495 from mouse GDF5, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~16kD (143aa) Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.