FCGR3A (Low Affinity Immunoglobulin gamma Fc Region Receptor III-A, CD16A)

Size

£438.00

SKU:: 218154
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to aa18-208 from human FCGR3A expressed in E. coli.
Clone:: 15B23
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 10% glycerol.
Extra Details:: FCGR3A (Low affinity immunoglobulin gamma Fc region receptor III-A), also known as CD16A, is a 254aa protein. This protein is involved in the removal of antigen-antibody complexes from the circulation, as well as other antibody-dependent responses. It is mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Hybridoma: F0 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.