CKMT1A (Ubiquitous Mitochondrial Creatine Kinase, Creatine Kinase, Mitochondrial 1A)

Size

£438.00

SKU:: 218039
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to aa40-417 from human CKMT1A expressed in E. coli.
Clone:: 15B12
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 10% glycerol.
Extra Details:: CKMT1A, also known as Creatine kinase, mitochondrial 1A, is a 417aa protein. Mitochondrial creatine kinase (MtCK) exists as two isoenzymes, sarcomeric MtCK (CKMT2) and ubiquitous MtCK (CKMT1). It is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Hybridoma: F0 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.