TCN-201 (3-Chloro-4-fluoro-N-[(4-{[2-(phenylcarbonyl)hydrazino]carbonyl}phenyl)methyl]benzenesulfonamide, NMDA Antagonist X)

Size

£442.00

SKU:: 217829
Molecular Weight:: 461.89
Purity:: ~98% (HPLC)
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 852918-02-6
Format:: Supplied as a white powder.
Extra Details:: A negative allosteric modulator selective for NR2A containingnMDA receptors (pIC50 = 6.8 and <4.3uM for NR2A and NR2B, respectively). No effect on NR2B-containingnMDA receptors with concentrations less than 50 mM. Inhibition on NR2A containingnMDA receptors is glycine (or D-serine)-binding, but not glutamate-binding, dependent. Formula: C21H17ClFN3O4S Solubility: DMSO Primary Target: NMDA receptors Molar Mass: 461.89 Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.