SR95531 (Gabazine) Hydrobromide

Size

£385.00

SKU:: 217808
Molecular Weight:: 368.23
Purity:: ≥98% (HPLC)
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 104104-50-9
Format:: White solid
Extra Details:: A selective, competitive antagonist of GABAA receptor (IC50 = 440nM) that does not affect pentobarbitone or etomidate- induced currents even at high concentrations (~100uM). Also shown to block glycine receptors, but with low affinity (Kb = 190uM). Synonyms: Gabazine; GABAA Receptor Antagonist; SR-95531; 6-imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid, monohydrobromide CAS No: 104104-50-9 Molecular Formula: C15H17N3O3 • HBr Molecular Weight: 368.23 Appearance: White solid Purity: ≥98% (HPLC) Primary Target: GABA-A Primary Target IC50: 440nM Proton NMR: Conforms to structure Elemental Analysis: C% :47.50-50.50% H%: 4.00-6.00% N%: 10.00-13.00% Water Molecules: ≤1.0mol Solubility: Water (25mM); MeOH:PBS (pH 7.2); (1:1): 0.5mg/ml; Methanol: 1mg/ml Storage and Stability: Lyophilized powder may be stored at 4°C Do not freeze. Stable for 6 months after receipt at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.