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217791

CAY10602

Size

£407.00

SKU:
217791
Molecular Weight:
418.4
Storage Conditions:
-20°C
Supplier:
United States Biological
CAS Number:
374922-43-7
Extra Details:
A cell-permeable pyrroloquinoxaline compound that acts as a reversible SIRT1 activator (10uM causes ~2.3-fold fluorescent enhancement in a fluorescent assay using hrSIRT1) and enhances fat mobilization in fully differentiated 3T3L1 fibroblasts. Shown to inhibit LPS-induced TNF-a release in THP-1 cells by ~10-fold more potent than resveratrol. Synonyms: 3-(Benzenesulfonyl)-1-(4-fluorophenyl)pyrrolo[4,5-b]quinoxalin-2-amine, SIRT1 Activator II CAS No: 374922-43-7 Molecular Formula: C₂₂H₁₅FN₄O₂S Molecular Weight: 418.4 Solubility: DMF, DMSO, DMSO:PBS, pH 7.2, (1:3): 0.25 mg/ml Appearance: Supplied as an off-white powder. Purity: ≥95% Storage and Stability: Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Shipping Conditions:
Blue Ice