RS 127445 Hydrochloride

Size

£388.00

SKU:: 217757
Purity:: ≥98% (HPLC)
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 199864-86-3
Format:: Supplied as an off-white solid.
Extra Details:: A selective, high affinity , orally bioavailable 5-HT2B receptor antagonist. RS-127445 was found to have nanomolar affinity for the 5-HT2B receptor (pKi = 9.5) and 1,000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites including the closely related 5-HT2A and 5-HT2C receptors. In isolated human cells, RS-127445 exbhited an IC50 greater than 10uM. CAS Number: 199864-86-3 Formula: C₁₇H₁₆FN₃·HCl Appearance: Supplied as an off-white solid. Solubility: DMSO or EtOH Primary Target: 5-HT2B Storage and Stability: Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.