Rolipram (4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone)

Size

£415.00

SKU:: 217751
Molecular Weight:: 275.4
Purity:: ≥98% (HPLC)
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 61413-54-5
Format:: Supplied as a white solid.
Extra Details:: A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50=800nM). A rolipram-insensitive PDE IV subtype is also known to exist. Also inhibits NF-kB and NFAT activation in Jurkat and primary T cells. Synonyms: 4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone CAS Number: 61413-54-5 Formula: C16H21NO3 Primary Target: PDE IV Primary Target IC50: 800nM Secondary Target: NF-kB and NFAT activation in Jurkat and primary T cells Solubility: DMSO Molecular Weight: 275.4 Storage and Stability: Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.