217675
PKR Inhibitor III, 7DG
Size
£448.00
- SKU:
- 217675
- Molecular Weight:
- 422.5
- Storage Conditions:
- 4°C
- Supplier:
- United States Biological
- CAS Number:
- 26927-01-5
- Extra Details:
- PKR inhibitor III is a nucleic acid molecule that inhibits PKR. It has been shown to be effective in transfecting cells and has therapeutic potential for use in treating patients with neutrophil disorders. PKR inhibitor III is an oligodeoxynucleotide that contains the sequence of 7-deaza-2'-deoxyguanosine (7dG). This sequence is complementary to the anti-sense strand of PKR mRNA and inhibits PKR activity by binding to its mRNA transcript. In vitro studies have shown that this nucleic acid molecule can inhibit PKR activity in tissue samples from patients with neutrophil disorders. Synonyms: 7-Desacetoxy-6,7-dehydrogedunin, Double-stranded RNA-dependent Protein Kinase Inhibitor III, Double-stranded RNA-activated Protein Kinase Inhibitor III, EIF2AK2 Inhibitor III CAS No: 26927-01-5 Molecular Formula: C₂₆H₃₀O₅ Molecular Weight: 422.5 Melting Point: 262°C Purity (HPLC): ≥95% 1H-NMR: Conforms to reference Appearance: Pale yellow solid. Storage and Stability: Store at 4°C under inert atmosphere. Stable for 6 months after receipt.
- Shipping Conditions:
- Blue Ice