Methylsticin

Size

£628.00

SKU:: 217586
Molecular Weight:: 274.27
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 495-85-2
Extra Details:: Methysticin has been identified from kava to have potent NF-kB inhibitory activity and minimum toxicity. It is shown to inhibit NF-kB (IC50 = 0.19ug/ml) 100 times more potently than traditional kava in A549 cells in an in vitro luciferase-based assay. It is also reported to suppress the elevation of IKKalpha, p65, and COX-2 and the degradation of IkBalpha in A549 cultures stimulated with TNF-alpha; through Western Blot analysis. Synonyms: (6R)-6-[(1E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-5,6- dihydro-4- methoxy-2H-pyran-2-one CAS No: 495-85-2 Molecular Formula: C₁₅H₁₄O₅ Molar Mass: 274.27 Solubility: DMSO Purity: ≥97% Storage and Stability: Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.